Supplementary MaterialsSupplementary Materials 41392_2020_170_MOESM1_ESM

Supplementary MaterialsSupplementary Materials 41392_2020_170_MOESM1_ESM. localization, transcriptional activity, and malignant transformation function of YAP. Moreover, the nuclear localization of YAP was enhanced in p190A-mutated endometrial cancer. These findings reveal novel molecular mechanisms underlying Hippo-YAP pathway-driven endometrial tumorigenesis and elucidate the potential for therapy targeting the Hippo-YAP pathway in p190A-mutated endometrial cancer. (N-cadherin), (E-cadherin), a well-known EMT… Continue reading Supplementary MaterialsSupplementary Materials 41392_2020_170_MOESM1_ESM