Magnified insets (white frames) show detail of primary cilia (arrowheads) in the embryo; 4V, fourth ventricle
Hydroxysteroid Dehydrogenase, 11??- 0 CommentsMagnified insets (white frames) show detail of primary cilia (arrowheads) in the embryo; 4V, fourth ventricle. pathognomonic for JBTS (including cerebellar hypoplasia), and retention of abnormal bulbous cilia associated with mild neural tube ventralization. The JBTS-like group TAS4464 had de-regulated low levels of canonical Wnt signalling associated with the loss of Dvl-1 localization to the