Introduction Nearly all autoimmune diseases such as rheumatoid arthritis (RA) and autoimmune thyroid diseases (AITDs) are characterized by a striking female predominance superimposed on a predisposing genetic background. useful controls (11.2%) (P < 0.0001; P = 0.0015, respectively). More importantly, extremely skewed XCI, defined as > 90% inactivation of one allele, 1314890-29-3 manufacture was present… Continue reading Introduction Nearly all autoimmune diseases such as rheumatoid arthritis (RA) and