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We report the case of the 25-year-old Iraqi girl who had multiple hospitalizations at another medical center for stomach discomfort, nausea, and diarrhea without the proof systemic lupus erythematosus. cyclophosphamide regimen, which led to significant radiological and clinical resolution. Keywords: lupus enteritis, SLE The differential for abdominal discomfort and diarrhea in systemic lupus erythematosus (SLE)

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