Supplementary Materials Supporting Information supp_293_16_6187__index. With a series of recombinant thalidomide-binding

Supplementary Materials Supporting Information supp_293_16_6187__index. With a series of recombinant thalidomide-binding domain (TBD) protein, we display that CRBN series variations preserve their drug-binding properties to both traditional immunomodulatory dBET1 and medications, a chemical substance compound and concentrating on ligand made to degrade bromodomain-containing 4 (BRD4) with a CRBN-dependent system. We further display that dBET1 stimulates… Continue reading Supplementary Materials Supporting Information supp_293_16_6187__index. With a series of recombinant thalidomide-binding