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History: Flavopiridol a semisynthetic flavone that prevents cyclin-dependent kinases (CDKs) and has growth-inhibitory activity and induces a blockade of cell-cycle development at G1-stage and apoptosis in many individual tumour cell lines and is currently under analysis in stage II scientific studies. cell and routine cytoskeleton in CSCs by RT-PCR. Outcomes: Flavopiridol-induced cytotoxicity and apoptosis at

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