Epidermal growth factor receptor (EGFR) mutations in non-small-cell lung cancer (NSCLC)

Epidermal growth factor receptor (EGFR) mutations in non-small-cell lung cancer (NSCLC) are predictive of response to treatment with tyrosine kinase inhibitors. Sequencing recognized rare mutations that are not identified by either castPCR or Therascreen, but in samples with low tumor cell content it failed to detect common mutations that were revealed by real-time PCR based… Continue reading Epidermal growth factor receptor (EGFR) mutations in non-small-cell lung cancer (NSCLC)