Supplementary Materials Supplementary Material supp_126_21_4843__index. the mitophagy E3-ligase Parkin (also known

Supplementary Materials Supplementary Material supp_126_21_4843__index. the mitophagy E3-ligase Parkin (also known as PARK2). Taken together, these data suggest that deacetylation of mitochondrial proteins initiates mitochondrial autophagy in a canonical autophagy-mediator-dependent program and shows that modulation of this regulatory program has ameliorative mitochondrial homeostatic effects. cDNA transfection is limited because SIRT3 overexpression results in deacetylation of… Continue reading Supplementary Materials Supplementary Material supp_126_21_4843__index. the mitophagy E3-ligase Parkin (also known