MAPK , 0 Comments

History and Purpose Highly vascularized ovarian carcinoma secretes the putative endocannabinoid and GPR55 agonist, L–lysophosphatidylinositol (LPI), in to the circulation. as ovarian carcinoma cell- and LPI-induced angiogenesis (Yoder and angiogenesis within an poultry chorioallantoic membrane (CAM) assay aswell as the root mechanisms. Focusing on the LPI/GPR55 axis could represent potential types of pro- and anti-angiogenic

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The proteasome is an essential cellular machine that maintains protein homeostasis, which is of particular importance in multiple myeloma and perhaps additional cancers. including those resistant to bortezomib. Proteomic evaluation exposed that capzimin stabilized a subset of polyubiquitinated substrates. Recognition of capzimin provides an alternative way to develop proteasome inhibitors for tumor therapy. Intro The

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