Supplementary MaterialsSupplemental data Supp_Data. non-human primates (NHPs), we attempt to investigate

Supplementary MaterialsSupplemental data Supp_Data. non-human primates (NHPs), we attempt to investigate whether such wide-spread manifestation could be improved after brainstem infusion. To increase delivery from the restorative transgene through the entire CNS, we mixed an individual brainstem infusion with bilateral thalamic infusions in naive NHPs. We discovered that enzymatic enhancement in brainstem, thalamic, cortical, aswell… Continue reading Supplementary MaterialsSupplemental data Supp_Data. non-human primates (NHPs), we attempt to investigate

Protein abundance and phosphorylation convey important information about pathway activity and

Protein abundance and phosphorylation convey important information about pathway activity and molecular pathophysiology in diseases including cancers providing biological insight informing drug and diagnostic development and guiding therapeutic intervention. and tissue-specific changes were observed. The demonstrated impact of pre-analytical tissue ischemia on tumor biology mandates caution in interpreting stress-pathway activation in such samples and motivates… Continue reading Protein abundance and phosphorylation convey important information about pathway activity and