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Supplementary MaterialsSupplementary Figures 41598_2019_48519_MOESM1_ESM. immunohistochemistry, we present that ephrin-A5 raises LMC growth cone Neogenin protein levels and netrin-1 binding. This effect is enhanced by overexpressing EphA4 and is inhibited by obstructing ephrin-A5-EphA4 binding. These effects have a functional result on LMC growth cone reactions since bath addition of ephrin-A5 increases the responsiveness of LMC axons

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