Three group of novel sulfonylurea podophyllotoxin derivatives were designed synthesized and evaluated for cytotoxicity against four tumor cell lines (A-549 DU-145 KB and KBvin). improve cytotoxic activity. family. It exerts cytotoxic activity by inhibiting microtubule assembly.1 2 Enormous progress has been achieved concerning the structural elements required for activity. These findings led to authorization of… Continue reading Three group of novel sulfonylurea podophyllotoxin derivatives were designed synthesized and