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Leptin is a peptide hormone that is characterized while the ligand of leptin receptor ((valueto reduce serum-stimulated H4IIE HCC cell proliferation [28]. AMPK activation [35]. cAMP elevation also shown the inhibitory impact to leptin-induced breasts tumor MDA-MB-231 migration that was along with a strong loss of 3 integrin subunit and focal adhesion kinase (FAK) proteins

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