Supplementary MaterialsSupplemental Figures 41419_2018_850_MOESM1_ESM. of APoptosis (cIAPs) ubiquitin ligases exerted a

Supplementary MaterialsSupplemental Figures 41419_2018_850_MOESM1_ESM. of APoptosis (cIAPs) ubiquitin ligases exerted a competent two times brake on apoptosis signaling. On the other hand, releasing only 1 of the two brakes was adequate to overcome the level of resistance of 8/8 tumor cell lines tested. Remarkably, the release of the c-FLIP, but not cIAPs, brake only results… Continue reading Supplementary MaterialsSupplemental Figures 41419_2018_850_MOESM1_ESM. of APoptosis (cIAPs) ubiquitin ligases exerted a