Background Hec1 (NDC80) is an integral part of the kinetochore and is overexpressed in a variety of human cancers making it an attractive molecular target for the design of novel anticancer therapeutics. blotting and immunofluorescent staining. The potency of TAI-1 was evaluated in three xenograft models in mice. Preliminary toxicity was evaluated in mice. Specificity… Continue reading Background Hec1 (NDC80) is an integral part of the kinetochore and