Mutations in the gene encoding transcription factor TFAP2A result in pigmentation anomalies in model organisms and premature hair graying in humans. from zebrafish. Paralogs and are both expressed in mouse melanocytes, and we show that mouse embryos with and in the neural crest almost completely lack melanocytes but retain neural crest-derived sensory ganglia. These results… Continue reading Mutations in the gene encoding transcription factor TFAP2A result in pigmentation