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Neural progenitor cells (NPCs) produced from human being pluripotent stem cells (hPSCs) certainly are a multipotent cell population that’s with the capacity of nearly indefinite expansion and following differentiation in to the several neuronal and accommodating cell types that comprise the CNS. Zhang et?al., 2008). Furthermore, these cells give a unique possibility to explore complicated

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The biguanide drug metformin is prescribed to take care of type 2 diabetes and metabolic syndrome widely, but its mode of action remains uncertain. in the nematode (Onken and Driscoll, 2010). The systems underlying these results stay unclear. One likelihood is normally that metformin recapitulates the consequences of dietary limitation (DR), the managed reduction of

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