Phenobarbital (PB), a non-genotoxic carcinogen, activates the nuclear constitutive active/androstane receptor

Phenobarbital (PB), a non-genotoxic carcinogen, activates the nuclear constitutive active/androstane receptor (CAR), resulting in the transcriptional induction or repression of various hepatic genes. are unknown in liver, we investigated the effects of TUBA8 gene manifestation on cell growth, proliferation and cell migration. Sense- or anti-sense cDNA for mouse TUBA8 (mTUBA8) was stably transfected into Huh7… Continue reading Phenobarbital (PB), a non-genotoxic carcinogen, activates the nuclear constitutive active/androstane receptor