Non-small cell lung malignancies (NSCLCs) harboring mutations in the epidermal growth

Non-small cell lung malignancies (NSCLCs) harboring mutations in the epidermal growth factor receptor (mutations predict sensitivity to EGFR tyrosine kinase inhibitors (TKIs) and thus represent a dependency in NSCLCs harboring these alterations but the genetic basis of EGFR dependence is not fully understood. achieved via EGFR activation in MET-dependent cells (13) and analogous examples of… Continue reading Non-small cell lung malignancies (NSCLCs) harboring mutations in the epidermal growth