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Background Cytochrome oxidase (COX) IV organic regulates energy creation in mitochondria. event (32.8%). Circulating Compact disc14+ monocytes and microvesicles had been isolated with magnetic beads, and COX mRNA amounts had been assessed with quantitative polymerase TAK-438 string response, after normalization with 5 TAK-438 validated home\keeping genes. Sufferers in the cheapest tertile of mitochondrial cytochrome oxidase,

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