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Leptin is a peptide hormone that is characterized while the ligand of leptin receptor ((valueto reduce serum-stimulated H4IIE HCC cell proliferation [28]. AMPK activation [35]. cAMP elevation also shown the inhibitory impact to leptin-induced breasts tumor MDA-MB-231 migration that was along with a strong loss of 3 integrin subunit and focal adhesion kinase (FAK) proteins

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Childhood obesity is one of the major health problems in western countries. thus resulting in osteoporosis. The purpose of this evaluate was to deepen the cellular mechanisms by which obesity may facilitate osteoporosis and bone fractures. insulin resistance in adipocytes. Therefore, taking into consideration the aftereffect of Path on adipose tissues using its pro-osteoclastogenic and

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