Apigenin a plant flavone potentially activates wild-type p53 and induces apoptosis in cancer cells. apigenin treatment. All these effects were significantly blocked by pretreatment of cells with the antioxidant into the cytosol [15 16 Cytochrome then binds to apoptosis protease-activating factor-1 (Apaf-1) and activates caspase-3 through caspase-9 resulting in execution of apoptosis [17]. Consequently regulation… Continue reading Apigenin a plant flavone potentially activates wild-type p53 and induces apoptosis