Objectives To look for the electrophysiologic effects of ranolazine in canine

Objectives To look for the electrophysiologic effects of ranolazine in canine pulmonary veins (PV) sleeve preparations. (BCL) from 2000 to 200 ms resulted in a decrease of Vmax from 27958 to 14623 V/s (47.7%) in control and from 24171 to 7263 V/s (70.2%) following 10 M ranolazine (n=4, p 0.05). Ranolazine slightly abbreviated action potential… Continue reading Objectives To look for the electrophysiologic effects of ranolazine in canine