MicroRNAs (miRNAs) play key tasks in modulating a variety of cellular

MicroRNAs (miRNAs) play key tasks in modulating a variety of cellular processes through repression of mRNAs target. with increased HbF synthesis. Therefore, our data indicate that miR-486-3p might contribute to different HbF levels observed among thalassemic individuals and, possibly, to the medical severity of the disease. Intro MicroRNAs (miRNAs) are a class of naturally happening,… Continue reading MicroRNAs (miRNAs) play key tasks in modulating a variety of cellular

Mutations in neurofilament light (NF-L) have been associated with Charcot-Marie-Tooth disease

Mutations in neurofilament light (NF-L) have been associated with Charcot-Marie-Tooth disease type 2E (CMT2E) in humans. NFs in motor neuron cell bodies as early as 1 month. Moreover Alarelin Acetate NF organization was altered in motor and sensory roots with small motor axons being most affected. Peak axonal diameter was reduced for small motor axons… Continue reading Mutations in neurofilament light (NF-L) have been associated with Charcot-Marie-Tooth disease