Increasing evidence revealed that miRNAs, the vital regulators of gene manifestation,

Increasing evidence revealed that miRNAs, the vital regulators of gene manifestation, are involved in various cellular processes, including cell growth, differentiation, apoptosis and progression. miR148b directly targeted mitogen-activated protein kinase (MAPK) kinase kinase 9 (MAP3K9), an BMS-650032 upstream activator of MAPK kinase/c-Jun N-terminal kinase (JNK) signaling, suppressing the protein but not the mRNA levels. Furthermore,… Continue reading Increasing evidence revealed that miRNAs, the vital regulators of gene manifestation,