We’ve reported a high expression of IGF-I in pancreatic islet β-cells

We’ve reported a high expression of IGF-I in pancreatic islet β-cells of transgenic mice under the metallothionein promoter. In freshly isolated islets the level of 11β-HSD1 protein was significantly lower in MT-IGF mice. Using dual-labeled immunofluorescence 11 was observed exclusively in glucagon-producing islet α-cells but at a lower level in transgenic vs. wild-type animals. MT-IGF… Continue reading We’ve reported a high expression of IGF-I in pancreatic islet β-cells

From HIV-Associated Nephropathy Prior to the arrival of effective antiviral therapy

From HIV-Associated Nephropathy Prior to the arrival of effective antiviral therapy AIDS was connected with extremely high mortality. in end-stage renal disease (ESRD) from HIVAN in america never have been described systematically. Methods The primary objectives of the research had been to enumerate developments in occurrence ratios standardized to 2001-2002 of ESRD from HIVAN treated… Continue reading From HIV-Associated Nephropathy Prior to the arrival of effective antiviral therapy