We designed and synthesized a classical analog an oxidative addition response

We designed and synthesized a classical analog an oxidative addition response using iodine. 1 could be attributed to elevated hydrophobic interaction from the 6-ethyl moiety of 4 and Val115 in individual DHFR as forecasted by molecular modeling. The elevated activity could also result from advantageous orientation from the 5-placement thioaryl side string that is even… Continue reading We designed and synthesized a classical analog an oxidative addition response