Aldo-keto reductase 1C3 (AKR1C3), also called type 5 17-hydroxysteroid dehydrogenase, is

Aldo-keto reductase 1C3 (AKR1C3), also called type 5 17-hydroxysteroid dehydrogenase, is normally a downstream steroidogenic enzyme and converts androgen precursors towards the potent androgen receptor ligands: testosterone and 5-dihydrotestosterone. Among these analogs, the inhibitory activity and selectivity of thirteen substances were examined for the very first time. The substitution from the 4-dihydrocinnamoyloxy band of baccharin… Continue reading Aldo-keto reductase 1C3 (AKR1C3), also called type 5 17-hydroxysteroid dehydrogenase, is