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Supplementary Materials1. disintegration of gastrointestinal crypts, stimulates the expression of adherens junction protein E-cadherin, activates crypt cell proliferation, and decreases apoptosis. TP508 post-exposure treatment also buy Exherin up-regulates the expression of DCLK1 and LGR5 markers of stem cells that have been been shown to be responsible for keeping and regenerating intestinal crypts. Therefore, TP508 seems

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