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The myelodysplastic syndromes (MDS) are a heterogeneous group of clonal myeloid haemopathies characterized by defective differentiation of hematopoietic cells and expansion of the abnormal clone. (14). An Italian group evaluated the prognostic value of the new WHO classification and showed that WHO morphologic subgroups, IPSS cytogenetic categories, and red blood cell (RBC) transfusion-dependency each had

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