Population stratification is one of the major causes of spurious associations

Population stratification is one of the major causes of spurious associations in association studies. association studies. Several approaches have been developed to deal with this problem. The genomic control [1], structured association [2,3], and principal-component analysis methods [4-8] correct for population stratification in population-based case-control studies by using a set of markers across the genome.… Continue reading Population stratification is one of the major causes of spurious associations