Major histocompatibility complex class II (MHCII) antigen expression is usually directly

Major histocompatibility complex class II (MHCII) antigen expression is usually directly correlated with immunogenicity, and inversely correlated with tumorigenicity, in clones of the L1210 murine B lymphoma. activate T cells. The costimulatory molecules B7-1, B7-2 and CD40 were expressed around the immunogenic L1210 clones, but not the tumorigenic clones. Importantly, the tumour-forming subclonal variants expressed… Continue reading Major histocompatibility complex class II (MHCII) antigen expression is usually directly