The biogenesis of the large (60S) ribosomal subunit in eukaryotes involves nucleolar, nucleoplasmic, and cytoplasmic steps. redundancy between Reh1 and Rei1, as a double deletion of and results in a synthetic growth defect (22), and overexpression of can partially suppress the pDEQ2 [or (including 300 nucleotides upstream and downstream, to include regulatory regions) from wild-type… Continue reading The biogenesis of the large (60S) ribosomal subunit in eukaryotes involves