Lysyl oxidase propeptide (LOX-PP) ectopic overexpression inhibits the growth of cancer

Lysyl oxidase propeptide (LOX-PP) ectopic overexpression inhibits the growth of cancer xenografts. 25 (p 0.05) and final tumor weight on day 25 (p 0.05) were observed with a reduced tumor growth rate of 60% after implantation. rLOX-PP significantly reduced the expression of proliferation markers and Erk1/2 MAP kinase activation, while prominent increases in apoptosis markers… Continue reading Lysyl oxidase propeptide (LOX-PP) ectopic overexpression inhibits the growth of cancer