ASXL1 is the obligate regulatory subunit of a deubiquitinase organic whose catalytic subunit is BAP1. six PCGF protein take action independently to form unique PRC1 complexes that have been named PRC1.1 to PRC1.6 based on the PCGF family member that constitutes the organic12. Canonical’ PRC1 complexes contain RING1A, RING1W, CBX protein and either PCGF2 or… Continue reading ASXL1 is the obligate regulatory subunit of a deubiquitinase organic whose