Myelin-associated glycoprotein (MAG) is definitely a sialic acid solution binding Ig-family

Myelin-associated glycoprotein (MAG) is definitely a sialic acid solution binding Ig-family lectin that functions in neuronal growth inhibition and stabilization of axon-glia interactions. from the NgR2 stalk, displays excellent binding of OMgp, Nogo-66, and MAG in comparison to wild-type NgR1 or NgR2. Soluble NgROMNI Rabbit polyclonal to Neurogenin1 (NgROMNI-Fc) binds highly to membrane destined inhibitors… Continue reading Myelin-associated glycoprotein (MAG) is definitely a sialic acid solution binding Ig-family

The cytosolic pathogen and causative agent of melioidosis has been shown

The cytosolic pathogen and causative agent of melioidosis has been shown to regulate IL-1 and IL-18 production through NOD-like receptor NLRP3 and pyroptosis via NLRC4. pathway of caspase-1 in macrophages was markedly reduced or completely abolished after illness with a flagellin FliC or a Capital t3SS3 BsaU mutant. Studies using cells transfected with the wild-type… Continue reading The cytosolic pathogen and causative agent of melioidosis has been shown