Background We previously reported a PI3K inhibitor “type”:”entrez-protein” attrs :”text”:”S14161″ term_id

Background We previously reported a PI3K inhibitor “type”:”entrez-protein” attrs :”text”:”S14161″ term_id :”98844″ term_text :”pirS14161 which displays a promising preclinical activity against multiple myeloma (MM) and leukemia but the chiral structure and poor solubility prevent its further application. and inhibition of PI3K were analyzed by flow cytometry and Western blotting respectively; anti-myeloma activity was performed on… Continue reading Background We previously reported a PI3K inhibitor “type”:”entrez-protein” attrs :”text”:”S14161″ term_id

Background Tumor tissues resembles chronically swollen tissues. resistant murine 67NR-Hyg mammary

Background Tumor tissues resembles chronically swollen tissues. resistant murine 67NR-Hyg mammary carcinoma cells were co-cultivated with puromycin resistant murine BMDCs from Tg(GFPU)5Nagy/J mice. Isolation of Tubacin hygromycin/puromycin resistant mBMDC/67NR-Hyg cell clones was performed by a dual drug selection process. PCR analysis Tubacin exposed an overlap of parental markers in mBMDC/67NR-Hyg cell clones suggesting that dual… Continue reading Background Tumor tissues resembles chronically swollen tissues. resistant murine 67NR-Hyg mammary