Angiotensin II (AngII) continues to be invoked being a primary mediator

Angiotensin II (AngII) continues to be invoked being a primary mediator for the advancement and development of both thoracic and stomach aortic aneurysms. certainly are a mixed band of pathologies which have the normal feature of long lasting dilation, which occur in the thoracic (TAAs) and stomach (AAAs) XL765 regions. Although AAAs and TAAs develop… Continue reading Angiotensin II (AngII) continues to be invoked being a primary mediator

Protein abundance and phosphorylation convey important information about pathway activity and

Protein abundance and phosphorylation convey important information about pathway activity and molecular pathophysiology in diseases including cancers providing biological insight informing drug and diagnostic development and guiding therapeutic intervention. and tissue-specific changes were observed. The demonstrated impact of pre-analytical tissue ischemia on tumor biology mandates caution in interpreting stress-pathway activation in such samples and motivates… Continue reading Protein abundance and phosphorylation convey important information about pathway activity and