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Background Sigma receptors, N-methyl-D-aspartate (NMDA) antagonist, and modulators of intracellular calcium mineral may be helpful for seizure control. (20 mg/kg) improved the latency for the PTZ-induced clonic (44%, P=0.021) and tonic-clonic (130.80%, P=0.043) seizures weighed 1245319-54-3 IC50 against the vehicle-treated group. Pets treated with opipramol (20 mg/kg) plus caffeine (200 mg/kg) got a considerably higher

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