Exon skipping is among several “steric blocking” applications of oligonucleotides (ONs)

Exon skipping is among several “steric blocking” applications of oligonucleotides (ONs) and their analogues that lately have undergone a renaissance and that have led to fresh therapeutic possibilities (Kurreck 2008 Kole et al. the splicing equipment. For drug utilize the ON must show additionally several other essential properties such as for example great biodistribution to… Continue reading Exon skipping is among several “steric blocking” applications of oligonucleotides (ONs)