Adenocarcinoma of the lung is the leading cause of cancer death worldwide. DNA and mRNA sequence from your same tumour highlighted splicing alterations driven by somatic genomic changes including exon 14 skipping in mRNA in 4% of instances. MAPK and PI(3)K pathway activity when measured at the protein level was explained by known mutations in… Continue reading Adenocarcinoma of the lung is the leading cause of cancer death